Grant-in-Aid for Transformative Research Areas (A)
The planned teams consist of eight principal investigators who work together to carry out the four steps; diorama construction, behavior measurement, behavior understanding, and algorithm verification.
The planned teams will mainly focus on biological species such as microalgae, sperm, bacteria, ciliates, and slime mold.
This team leaders are Dr. Shikata, who is investigating the diurnal vertical migration of harmful red tide algae in Diorama and Panoramic environments, and Dr. Shiba, who is studying the flagellar motion of sperm as they change direction toward the egg. They are responsible for supplying experimental data to other groups, as needed.
Elucidation of the Accumulation Algorithm of Harmful Red Tide Algae in Diorama and Panoramic environments
Response measurement and regulatory mechanism of sperm chemotaxis in Diorama environments
This team leaders are Dr. Shinohara, who is measuring structure-motion interaction of sperm flagella and tracheal cilia from molecular to tissue scale, and Dr. Kikuchi, who is conducting in vivo visualization measurement of zebrafish intestine. We will support the fabrication of experimental apparatuses for other groups, including open research.
Proto-intelligence of mammalian airway ciliated cells in response to Diorama environmental changes.
Development of an in vivo 4D-X-ray tomographic visualization method for dense microorganisms in Diorama environments.
Mechanical Modeling Team (B01) consists of Dr. Ishikawa, who is studying behavioral algorithms of ciliates, and Dr. Ishimoto, who is constructing mathematical models of sperm chemotaxis. Using the methods of biophysics and applied mathematics, the team will mechanically model the responses of various microorganisms, cell-cell interactions, and cell-environment interactions.
Development of an Ethological Simulator Based on Microorganism Dynamics in Physical Environments.
Environment-coupled mechanical models for morphogenesis, reproduction, ecology and evolution of microalgae.
The Algorithm Evaluation Group (B02) consists of Dr. Nakagaki, who is working on the algorithm of slime mold to find the shortest path in a maze, and Dr. Iima, who is working on the models of collective motion of microalgae. We will evaluate the algorithms proposed by other groups including Publicly Offered Research groups, and provide feedbacks to each research project.
Algorithms for Collective Space Exploration and Space Utilization in Ciliates and Amoebae
Crosstalk algorithms between microbial behavior and the environment
Ethological dynamics in diorama environments